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summary{cursor:pointer;list-style:none;font-weight:700;color:var(--gv3-ink);display:flex;justify-content:space-between;align-items:center;gap:10px;font-size:15px}\n.guidaio-v3 .faq summary::-webkit-details-marker{display:none}\n.guidaio-v3 .faq summary svg{color:var(--gv3-brand)}\n.guidaio-v3 .faq .ans{color:var(--gv3-muted);margin-top:10px;font-size:14px}\n.guidaio-v3 section.block.conclusion{background:radial-gradient(700px 320px at 0% 0%,rgba(124,99,255,.18),transparent 60%),linear-gradient(135deg,#1c163a 0%,#2c1d8a 100%);color:#fff;border-color:#2c1d8a}\n.guidaio-v3 section.block.conclusion .head h2{color:#fff}\n.guidaio-v3 section.block.conclusion .lead,.guidaio-v3 section.block.conclusion .rich p{color:rgba(255,255,255,.88)}\n.guidaio-v3 section.block.conclusion .rich strong,.guidaio-v3 section.block.conclusion .rich b{color:#fff}\n.guidaio-v3 section.block.conclusion .eyebrow{background:rgba(255,255,255,.14);color:#fff}\n.guidaio-v3 section.block.conclusion .btn-secondary{background:rgba(255,255,255,.14);color:#fff;border-color:rgba(255,255,255,.25)}\n@media (max-width:1080px){.guidaio-v3 .hero-grid,.guidaio-v3 .trust-grid,.guidaio-v3 .company-grid,.guidaio-v3 .setup-grid,.guidaio-v3 .availability{grid-template-columns:1fr}.guidaio-v3 .grid-3,.guidaio-v3 .res-grid,.guidaio-v3 .plan-grid{grid-template-columns:repeat(2,minmax(0,1fr))}}\n@media (max-width:700px){.guidaio-v3{padding:12px 8px 48px}.guidaio-v3 .hero{padding:20px}.guidaio-v3 section.block{padding:20px}.guidaio-v3 .grid-2,.guidaio-v3 .grid-3,.guidaio-v3 .res-grid,.guidaio-v3 .plan-grid,.guidaio-v3 .bestnot,.guidaio-v3 .availability{grid-template-columns:1fr}.guidaio-v3 h1.title{font-size:28px}}\n\u003c\/style\u003e\n\u003cdiv class=\"guidaio-v3\" itemscope itemtype=\"https:\/\/schema.org\/SoftwareApplication\"\u003e\n\u003cmeta itemprop=\"name\" content=\"X-RAIS: AI Medical Image Analysis for Radiology Teams\"\u003e\n\u003cmeta itemprop=\"description\" content=\"X-RAIS by Laife Reply analyses mammograms, chest X-rays and brain MRI with AI, flagging lesions and drafting reports inside your PACS. No public pricing.\"\u003e\n\u003cdiv class=\"hero\"\u003e\u003cdiv class=\"hero-grid\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"hero-head\"\u003e\n\u003cdiv class=\"logo-tile\"\u003e\u003cimg src=\"https:\/\/www.reply.com\/contents\/logoreply.png\" alt=\"X-RAIS logo\" itemprop=\"image\" loading=\"lazy\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"name-block\"\u003e\n\u003cspan class=\"eyebrow\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpath d=\"m12 3-1.9 5.8a2 2 0 0 1-1.3 1.3L3 12l5.8 1.9a2 2 0 0 1 1.3 1.3L12 21l1.9-5.8a2 2 0 0 1 1.3-1.3L21 12l-5.8-1.9a2 2 0 0 1-1.3-1.3Z\"\u003e\u003c\/path\u003e\u003c\/svg\u003e Healthcare Medical Scribes · Report Generation\u003c\/span\u003e\u003ch1 class=\"title\" itemprop=\"name\"\u003eX-RAIS\u003c\/h1\u003e\n\u003cp class=\"lede justify\" itemprop=\"description\"\u003eX-RAIS is a medical image analysis AI platform from \u003cb\u003eLaife Reply\u003c\/b\u003e that reads mammograms, chest X-rays and brain MRI scans, flags suspicious findings and drafts reports for radiologists inside existing PACS and RIS workflows.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"badge-row\"\u003e\n\u003cspan class=\"badge ok\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"10\"\u003e\u003c\/circle\u003e\u003cpath d=\"m9 12 2 2 4-4\"\u003e\u003c\/path\u003e\u003c\/svg\u003e Active\u003c\/span\u003e\u003cspan class=\"badge ok\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpath d=\"M12 22s8-4 8-10V5l-8-3-8 3v7c0 6 8 10 8 10z\"\u003e\u003c\/path\u003e\u003cpath d=\"m9 12 2 2 4-4\"\u003e\u003c\/path\u003e\u003c\/svg\u003e GDPR compliant\u003c\/span\u003e\u003cspan class=\"badge\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpath d=\"M6.3 20.3a2.4 2.4 0 0 0 3.4 0L12 18l-6-6-2.3 2.3a2.4 2.4 0 0 0 0 3.4Z\"\u003e\u003c\/path\u003e\u003cpath d=\"m2 22 3-3\"\u003e\u003c\/path\u003e\u003cpath d=\"M7.5 13.5 10 11\"\u003e\u003c\/path\u003e\u003cpath d=\"M10.5 16.5 13 14\"\u003e\u003c\/path\u003e\u003cpath d=\"m18 3-4 4h6l-4 4\"\u003e\u003c\/path\u003e\u003c\/svg\u003e No public API\u003c\/span\u003e\u003cspan class=\"badge brand\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"10\"\u003e\u003c\/circle\u003e\u003cpath d=\"m9 12 2 2 4-4\"\u003e\u003c\/path\u003e\u003c\/svg\u003e Verified by Guidaio\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"tbd-row\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"label\"\u003eCategories\u003c\/div\u003e\n\u003cdiv class=\"chip-row\"\u003e\n\u003ca class=\"chip cat\" href=\"\/collections\/healthcare-medical-scribes\"\u003eHealthcare Medical Scribes\u003c\/a\u003e\u003ca class=\"chip cat\" href=\"\/collections\/report-generation\"\u003eReport Generation\u003c\/a\u003e\u003ca class=\"chip cat\" href=\"\/collections\/workflow-automation\"\u003eWorkflow Automation\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"label\"\u003eTarget domains\u003c\/div\u003e\n\u003cdiv class=\"chip-row\"\u003e\n\u003ca class=\"chip dom\" href=\"\/collections\/healthcare-medicine\"\u003eHealthcare Medicine\u003c\/a\u003e\u003ca class=\"chip dom\" href=\"\/collections\/biotech-pharma\"\u003eBiotech Pharma\u003c\/a\u003e\u003ca class=\"chip dom\" href=\"\/collections\/science-r-d\"\u003eScience R D\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"cta-row\"\u003e\u003ca class=\"btn btn-primary\" href=\"https:\/\/www.reply.com\/en\/healthcare\/x-rais\" target=\"_blank\" rel=\"noopener\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"16\" height=\"16\"\u003e\u003cpath d=\"M15 3h6v6\"\u003e\u003c\/path\u003e\u003cpath d=\"M10 14 21 3\"\u003e\u003c\/path\u003e\u003cpath d=\"M18 13v6a2 2 0 0 1-2 2H5a2 2 0 0 1-2-2V8a2 2 0 0 1 2-2h6\"\u003e\u003c\/path\u003e\u003c\/svg\u003e Discover the X-RAIS platform\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003caside class=\"snapshot\"\u003e\u003ch3\u003eSnapshot\u003c\/h3\u003e\n\u003cdl\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdt\u003eAPI available\u003c\/dt\u003e\n\u003cdd\u003eNo\u003c\/dd\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdt\u003eDeployment\u003c\/dt\u003e\n\u003cdd\u003eAPI\u003c\/dd\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdt\u003eTool status\u003c\/dt\u003e\n\u003cdd\u003eActive\u003c\/dd\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdt\u003eCountry of origin\u003c\/dt\u003e\n\u003cdd\u003e🇮🇹 Italy\u003c\/dd\u003e\n\u003c\/div\u003e\n\u003c\/dl\u003e\u003c\/aside\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cnav class=\"toc\" aria-label=\"Page sections\"\u003e\u003ca href=\"#what\"\u003eWhat is it\u003c\/a\u003e\u003ca href=\"#bestnot\"\u003eWhen to use X-RAIS \/ When not to\u003c\/a\u003e\u003ca href=\"#how\"\u003eHow to use\u003c\/a\u003e\u003ca href=\"#proscons\"\u003ePros \u0026amp; Cons\u003c\/a\u003e\u003ca href=\"#pricing\"\u003ePricing\u003c\/a\u003e\u003ca href=\"#trust\"\u003eTrust \u0026amp; Privacy\u003c\/a\u003e\u003ca href=\"#watch\"\u003eWatch-outs\u003c\/a\u003e\u003ca href=\"#setup\"\u003eSetup \u0026amp; Integrations\u003c\/a\u003e\u003ca href=\"#company\"\u003eCompany\u003c\/a\u003e\u003ca href=\"#resources\"\u003eResources\u003c\/a\u003e\u003ca href=\"#faq\"\u003eFAQ\u003c\/a\u003e\u003ca href=\"#conclusion\"\u003eConclusion\u003c\/a\u003e\u003c\/nav\u003e\n\u003csection class=\"block\" id=\"what\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eOverview\u003c\/span\u003e\u003ch2\u003eWhat is X-RAIS?\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"grid-2\"\u003e\n\u003cdiv class=\"rich justify\"\u003e\n\u003cp\u003e\u003cb\u003eX-RAIS\u003c\/b\u003e is a medical image analysis AI platform based on neural networks and radiomics, developed by \u003cb\u003eLaife Reply\u003c\/b\u003e, the healthcare unit of the Italian group Reply. Rather than one general-purpose model, it is verticalised: specialised by diagnostic method, such as radiography, ultrasound, CT and MRI, and by specific anatomical region. Its declared role is that of a \u003ci\u003ecognitive assistant\u003c\/i\u003e supporting physicians at the diagnosis and reporting stages, with the stated aim of reducing the number of misdiagnoses and improving the efficiency of the whole diagnostic process. It is not presented as an autonomous decision system.\u003c\/p\u003e\n\u003cp\u003eThree specialisations are described as delivered. Mammography came first, built with the scientific partners IRCCS IEO, ICS Maugeri and ULLS2 Marca Trevigiana, with dedicated models for suspicious microcalcifications, radio-opacities and suspicious breast lesions; the page notes that breast cancer is the most frequent cancer in women, at 30.3% according to AIRC. The second is chest radiography, developed inside the ALFABETO project on Covid-19 with ICS Maugeri and the University of Pavia, aimed at triaging symptomatic patients at home, combining the image with instrumental and anamnestic data to grade severity. The third is 3D brain MRI, where the platform segments glioma and classifies its severity. Histopathology imaging and the identification of new biomarkers are described as research and development, on a path towards precision medicine.\u003c\/p\u003e\n\u003cp\u003eArchitecturally, the platform is a set of technology modules, APIs and Web Services, that connect to diagnostic systems such as RIS and PACS through DICOM node integration, alongside anonymisation and sensitive-data protection routines and vertical modules for value-based healthcare. Images acquired by diagnostic equipment are analysed and the identified lesions and reports are sent back to the PACS, while examinations returning a suspicious result are automatically escalated in priority for specialist staff. A July 2025 announcement adds a multi-agent system: one agent helps generate the report enriched with the patient's history, a second assigns scores to prioritise the most critical cases, and integration with existing healthcare systems is described through APIs compliant with FHIR standards.\u003c\/p\u003e\n\u003cp\u003eCognitive and AI services are delivered through cloud architectures, with on-prem installation or use possible in specific cases. The design is explicitly \u003ci\u003ehuman-in-the-loop\u003c\/i\u003e: the radiologist stays at the centre of the process. The product page itself was published in December 2023.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch3 style=\"font-size:14px;margin-bottom:12px;color:var(--gv3-brand-ink);text-transform:uppercase;letter-spacing:.08em\"\u003eWhat it does\u003c\/h3\u003e\n\u003cul class=\"brand-list\"\u003e\n\u003cli\u003eAutomatically analyse medical images acquired by diagnostic equipment\u003c\/li\u003e\n\u003cli\u003eFlag and classify suspicious areas: microcalcifications, radio-opacities and suspicious breast lesions\u003c\/li\u003e\n\u003cli\u003eSegment glioma on 3D brain MRI and classify its severity\u003c\/li\u003e\n\u003cli\u003eGrade the severity of a condition from a chest X-ray combined with clinical data\u003c\/li\u003e\n\u003cli\u003eReturn identified lesions and reports to the PACS\u003c\/li\u003e\n\u003cli\u003eAutomatically raise the priority of examinations with a suspicious result, for smart triage\u003c\/li\u003e\n\u003cli\u003eAssist report writing by drawing on the patient's history\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block soft\" id=\"bestnot\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eAudience\u003c\/span\u003e\u003ch2\u003eWhen to use X-RAIS \/ When not to\u003c\/h2\u003e\n\u003cp class=\"lead\"\u003eA quick filter to help you decide if X-RAIS is the right fit.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"bestnot\"\u003e\n\u003cdiv class=\"card for\"\u003e\n\u003ch3\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"16\" height=\"16\"\u003e\u003cpath d=\"M7 10v12\"\u003e\u003c\/path\u003e\u003cpath d=\"M15 5.88 14 10h5.83a2 2 0 0 1 1.92 2.56l-2.33 8A2 2 0 0 1 17.5 22H4a2 2 0 0 1-2-2v-8a2 2 0 0 1 2-2h2.76a2 2 0 0 0 1.79-1.11L12 2a3.13 3.13 0 0 1 3 3.88Z\"\u003e\u003c\/path\u003e\u003c\/svg\u003e When to use X-RAIS\u003c\/h3\u003e\n\u003cul class=\"brand-list\"\u003e\n\u003cli\u003eHigh-volume radiology and diagnostic imaging departments where the number of examinations outpaces the available reading time\u003c\/li\u003e\n\u003cli\u003eOrganised mammography screening programmes looking for support on microcalcifications, radio-opacities and suspicious breast lesions\u003c\/li\u003e\n\u003cli\u003eHospitals already running a PACS and a RIS, with the IT capability to host an additional DICOM node\u003c\/li\u003e\n\u003cli\u003eIRCCS research hospitals, public and private hospitals and health authorities, the customer profile Laife Reply describes for its healthcare unit\u003c\/li\u003e\n\u003cli\u003eClinical research teams working with scientific partners, in the mould of IRCCS IEO, ICS Maugeri, ULLS2 Marca Trevigiana and the University of Pavia\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"card not\"\u003e\n\u003ch3\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"16\" height=\"16\"\u003e\u003cpath d=\"M17 14V2\"\u003e\u003c\/path\u003e\u003cpath d=\"M9 18.12 10 14H4.17a2 2 0 0 1-1.92-2.56l2.33-8A2 2 0 0 1 6.5 2H20a2 2 0 0 1 2 2v8a2 2 0 0 1-2 2h-2.76a2 2 0 0 0-1.79 1.11L12 22a3.13 3.13 0 0 1-3-3.88Z\"\u003e\u003c\/path\u003e\u003c\/svg\u003e When not to use X-RAIS\u003c\/h3\u003e\n\u003cul class=\"brand-list\"\u003e\n\u003cli\u003ePatients and members of the public: X-RAIS is built for medical staff and has no consumer-facing access\u003c\/li\u003e\n\u003cli\u003eAnyone hoping to sign up online, since there is no self-service account, no trial and no self-deployment; every engagement goes through Reply\u003c\/li\u003e\n\u003cli\u003eTeams needing modalities beyond the three delivered specialisations, as histopathology imaging is still described as research and development\u003c\/li\u003e\n\u003cli\u003eDepartments looking to automate reporting without a clinician in the loop: the human-in-the-loop design deliberately keeps the radiologist responsible\u003c\/li\u003e\n\u003cli\u003eBuyers who must budget from a published price list, because no amount is public and every engagement has to be quoted\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block soft\" id=\"how\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eGet started\u003c\/span\u003e\u003ch2\u003eHow to use X-RAIS\u003c\/h2\u003e\n\u003cp class=\"lead\"\u003eA typical end-to-end flow, from setup to results.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003col class=\"steps\"\u003e\n\u003cli\u003eCheck the fit first: X-RAIS is sold to institutions, and the delivered specialisations are mammography, chest radiography and 3D brain MRI\u003c\/li\u003e\n\u003cli\u003eMake contact through the Laife Reply contact form or the Reply contacts page, since there is no online sign-up and no self-service account\u003c\/li\u003e\n\u003cli\u003eScope the project with Laife Reply, including which vertical modules apply and whether cloud or on-prem use is appropriate\u003c\/li\u003e\n\u003cli\u003eAgree commercial terms directly with Reply: usage is offered on a pay-per-use or periodic subscription basis, with nothing quoted publicly\u003c\/li\u003e\n\u003cli\u003ePlan the integration with hospital IT and medical physics, as X-RAIS connects to the RIS and PACS through DICOM node integration\u003c\/li\u003e\n\u003cli\u003eConnect the technology modules, APIs and Web Services, and where relevant the FHIR-compliant APIs to existing healthcare systems\u003c\/li\u003e\n\u003cli\u003eRoute the images acquired by diagnostic equipment to the platform for automatic analysis\u003c\/li\u003e\n\u003cli\u003eCollect the identified lesions and generated reports back in the PACS, where radiologists read them in their usual environment\u003c\/li\u003e\n\u003cli\u003eRely on smart triage: examinations with a suspicious result are automatically promoted to high priority for specialist staff\u003c\/li\u003e\n\u003cli\u003eKeep the radiologist in the loop, with the reporting and scoring agents acting as support rather than as the decision-maker\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e\n\u003csection class=\"block\" id=\"proscons\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eQuick read\u003c\/span\u003e\u003ch2\u003ePros \u0026amp; Cons\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"grid-2\"\u003e\n\u003cdiv class=\"pc pros\"\u003e\n\u003ch3\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"10\"\u003e\u003c\/circle\u003e\u003cpath d=\"m9 12 2 2 4-4\"\u003e\u003c\/path\u003e\u003c\/svg\u003e Pros\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/svg\u003e \u003cspan\u003eBacked by a listed European group: Reply S.p.A. trades on the Euronext STAR Milan segment (ISIN IT0005282865, ticker REY) and reports more than 17,200 people across 16 countries\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/svg\u003e \u003cspan\u003eClinical grounding through named partnerships with IRCCS IEO, ICS Maugeri, ULLS2 Marca Trevigiana and the University of Pavia\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/svg\u003e \u003cspan\u003eThree distinct specialisations already delivered, across three different imaging modalities\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/svg\u003e \u003cspan\u003eDesigned to sit inside the existing workflow through PACS, RIS, DICOM and FHIR, rather than as an isolated tool\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/svg\u003e \u003cspan\u003eExplicit human-in-the-loop approach that keeps the radiologist as the decision-maker\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/svg\u003e \u003cspan\u003eOn-prem installation or use possible in specific cases, for institutions that cannot move data outside their own walls\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/svg\u003e \u003cspan\u003eEuropean publisher with a controller established in Italy and designated DPOs, plus a first-party scientific publication on microcalcification annotation available as a PDF\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pc cons\"\u003e\n\u003ch3\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"16\" height=\"16\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"10\"\u003e\u003c\/circle\u003e\u003cline x1=\"4.93\" y1=\"4.93\" x2=\"19.07\" y2=\"19.07\"\u003e\u003c\/line\u003e\u003c\/svg\u003e Cons\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/svg\u003e \u003cspan\u003eNo public pricing of any kind: no amount, no price grid and no pricing page, checked across the 1,395 URLs of the English sitemap and on both the English and Italian product pages\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/svg\u003e \u003cspan\u003eNo free trial and no openly accessible demonstration; the only way in is a contact form\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/svg\u003e \u003cspan\u003eNo API documentation is published, even though the platform advertises API and Web Services modules and FHIR-compliant APIs\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/svg\u003e \u003cspan\u003eNo privacy policy and no data processing agreement specific to the product: the site's legal documents cover the website and the client relationship, not the processing of clinical data\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/svg\u003e \u003cspan\u003eNo hosting country or region is disclosed and no subprocessor list is published\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/svg\u003e \u003cspan\u003eNo certification such as ISO or SOC 2, no CE marking and no medical device status is mentioned on the product page, and no interface language is declared\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/svg\u003e \u003cspan\u003eThe contracting entity is never named, the Privacy Notice (Client) referring only to \"the Reply Group's Company, holder of the contractual relationship\", and the product page has not been dated since December 2023, the most recent item being a July 2025 announcement\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block soft\" id=\"pricing\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003ePricing\u003c\/span\u003e\u003ch2\u003ePricing \u0026amp; Plans\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cp class=\"rich justify\" style=\"color:var(--gv3-ink-2);margin:0 0 18px;max-width:80ch\"\u003eNo price is published for X-RAIS anywhere on reply.com: neither the English nor the Italian product page carries an amount, and the site has no pricing page. The publisher states only that the platform \"can be used on a pay-per-use or periodic subscription basis\", without designating either arrangement as the standard one, and adds that in certain cases the architecture also allows on-prem installation or use. There is no free plan and no free trial. A budget can therefore only be established through a quotation obtained directly from Reply.\u003c\/p\u003e\n\u003cdiv class=\"pricing-extras\"\u003e\u003cdiv class=\"affiliate-note\"\u003ePrices and plans listed above may evolve. Always check the official pricing page before subscribing.\u003c\/div\u003e\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block\" id=\"trust\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eTrust \u0026amp; Privacy\u003c\/span\u003e\u003ch2\u003eData, GDPR \u0026amp; hosting\u003c\/h2\u003e\n\u003cp class=\"lead\"\u003eA consolidated view of how X-RAIS handles your data.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"trust-grid\"\u003e\n\u003cdiv class=\"col\"\u003e\n\u003cdiv class=\"trust-card\"\u003e\n\u003ch3\u003eGDPR overview\u003c\/h3\u003e\n\u003cp class=\"justify\" style=\"color:var(--gv3-ink-2);margin:0\"\u003eGDPR compliance is asserted at publisher and website level, never in a document specific to X-RAIS. The product page carries a single sentence: X-RAIS \"guarantees data integrity and confidentiality, which are crucial in light of the new privacy regulations in force (GDPR)\". Behind it sits the group's apparatus: a controller established in Italy, so no Article 27 representative is required, and three designated DPOs, dpo.it@reply.it for Italy, dpo.de@reply.de for Germany and Poland, dpo.uk@reply.com for the United Kingdom. The Privacy Notice (Client), issued pursuant to Section 13 of the EU and UK GDPR and last updated in November 2022, lists access, erasure, rectification, integration, restriction, objection and complaint to a supervisory authority; rights are exercised at client.privacy@reply.com, and at marketing.privacy@reply.com for the site, whose Privacy and Cookie Policy dates from December 2025. No product-specific DPA is published.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"trust-card\"\u003e\n\u003ch3\u003eWho owns the data?\u003c\/h3\u003e\n\u003cp class=\"justify\" style=\"color:var(--gv3-ink-2);margin:0 0 12px\"\u003eNo privacy policy is published for X-RAIS itself, so no document sets out who owns or controls the clinical images an institution would process. Two site-level documents exist. The Reply Website\/Platform Privacy and Cookie Policy, last updated in December 2025, names \u003cb\u003eReply S.p.A.\u003c\/b\u003e, registered office Corso Francia 110, Turin, as data controller, and covers the reply.com website only. The Privacy Notice (Client), last updated in November 2022, designates as controller \"the Reply Group's Company, holder of the contractual relationship\" with the client, without ever naming that entity, and concerns client contact data rather than patient imaging. On the product side, the only published statement is that the architecture includes routines for anonymisation and protection of sensitive data.\u003c\/p\u003e\n\u003ch3\u003eReuse rights\u003c\/h3\u003e\n\u003cp class=\"justify\" style=\"color:var(--gv3-ink-2);margin:0\"\u003eThe website policy describes technical, profiling and techno-functional cookies plus ZoomInfo company identification, with prior consent required for profiling. The Privacy Notice (Client) covers contact data of the client's employees and contractors, processed to perform the contract, meet legal obligations and pursue the group's legitimate interest. Neither document says anything about what happens to the clinical images a hospital would submit through X-RAIS. The models themselves were trained on anonymised clinical data supplied by named scientific partners, not by customers: Reply states that several scientific partners provided \"both the anonymized clinical data and the know-how for its annotation\". No commitment is published on whether customer data is or is not used for training, and no opt-out mechanism is documented. Reuse rights over analysis outputs are not addressed anywhere in public, and there are no terms and conditions on the site to settle the question.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"trust-card\"\u003e\n\u003ch3\u003eData retention \u0026amp; training\u003c\/h3\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eRetention summary\u003c\/div\u003e\n\u003cdiv class=\"v justify\"\u003eNo retention period is published for X-RAIS itself: nothing states how long clinical images or analysis results are kept, or when they are deleted. The only stated rule sits in the Privacy Notice (Client) of November 2022 and concerns a different data set, the contact data of the client's employees and contractors, which is processed for the entire duration of the contractual relationship and, after it ends, for the maximum period provided by applicable statutory limitation and by legal and tax time limits. No figure in months or years is given, and the notice invites clients to request further detail from the controller or the Data Protection Officer. The website's Privacy and Cookie Policy, updated in December 2025, contains no retention table either and routes cookie retention questions to marketing.privacy@reply.com.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eGDPR contact\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003e\u003ca href=\"mailto:dpo.it@reply.it\"\u003edpo.it@reply.it\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"col\"\u003e\u003cdiv class=\"trust-card\"\u003e\n\u003ch3\u003eHosting summary\u003c\/h3\u003e\n\u003cp class=\"justify\" style=\"color:var(--gv3-ink-2);margin:0 0 14px\"\u003eNo hosting country and no hosting region is announced for X-RAIS. The only published facts are that cognitive and artificial intelligence services are offered through cloud architectures and that, in certain cases, the specific architecture of the platform also allows on-prem installation or use, which means clinical data can in principle remain inside the institution, subject to project scoping. No cloud provider is named, no data centre location is given, and no subprocessor list is available. The only jurisdiction that can be established is that of the publisher rather than of the data: Reply is established in Italy, and the controller named for the reply.com website is Reply S.p.A., with a registered office in Turin. One point deserves care. The reply.com website itself is served from an AWS IP address located in Ireland (99.80.3.188), but that is an infrastructure fact about the corporate website and says nothing about where clinical images processed by X-RAIS would be stored. For a hospital, hosting location and data residency have to be obtained contractually from the publisher; they cannot be read off the public pages.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block watch\" id=\"watch\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eWatch-outs\u003c\/span\u003e\u003ch2\u003eThings to keep in mind\u003c\/h2\u003e\n\u003cp class=\"lead\"\u003eRisks and trade-offs to weigh before adopting X-RAIS.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cul class=\"brand-list\" style=\"grid-template-columns:repeat(2,1fr);display:grid;gap:12px 24px\"\u003e\n\u003cli\u003eThe budget cannot be estimated before a quotation: no amount is published, and both announced arrangements, pay-per-use and periodic subscription, are left unpriced\u003c\/li\u003e\n\u003cli\u003eThe contracting legal entity is never named; the Privacy Notice (Client) points only to \"the Reply Group's Company, holder of the contractual relationship\", which must be pinned down before signature\u003c\/li\u003e\n\u003cli\u003eNo CE marking, medical device status or security certification such as ISO 27001 or SOC 2 is mentioned for X-RAIS, a decisive point for diagnostic support software in Europe\u003c\/li\u003e\n\u003cli\u003eNo privacy policy or data processing agreement covers the product itself, leaving the processing of clinical images contractually undefined by the public documents\u003c\/li\u003e\n\u003cli\u003eNo hosting country or region is announced, even though health data is at stake, and no subprocessor list is available for a vendor security assessment\u003c\/li\u003e\n\u003cli\u003eAPIs are advertised but no documentation is published, so the true integration effort cannot be assessed before the project starts\u003c\/li\u003e\n\u003cli\u003eAutomation bias is the human risk to manage: smart triage scores and generated reports are only safe if readers keep questioning the flags instead of deferring to them, and since the product page dates from December 2023, the current state of the specialisations should be confirmed with the publisher\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/section\u003e\n\u003csection class=\"block\" id=\"setup\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eSetup\u003c\/span\u003e\u003ch2\u003eSetup \u0026amp; Integrations\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"setup-grid\"\u003e\u003cdiv class=\"setup-card\"\u003e\n\u003ch3 style=\"font-size:15px;margin-bottom:10px\"\u003eTechnical difficulty\u003c\/h3\u003e\n\u003cp class=\"justify\" style=\"color:var(--gv3-ink-2);margin:0 0 14px\"\u003eThis is a system integration, not a software installation. X-RAIS connects to the institution's PACS and RIS through DICOM node integration, exposes API and Web Services modules, and offers FHIR-compliant APIs for connection to existing healthcare systems; on-prem installation or use is possible in specific cases. There is no self-service path: deployment runs as a project with Laife Reply, and no public technical documentation exists to prepare the work beforehand. Expect to involve hospital IT, the PACS and RIS administrators and information security, and to plan the integration jointly with the publisher.\u003c\/p\u003e\n\u003ch3 style=\"font-size:15px;margin:14px 0 10px\"\u003eDeployment\u003c\/h3\u003e\n\u003cdiv class=\"flag-row\"\u003e\u003cspan class=\"flag\"\u003eAPI\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block soft\" id=\"company\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eCompany\u003c\/span\u003e\u003ch2\u003eBehind X-RAIS\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"company-grid\"\u003e\n\u003cdiv class=\"company-card\"\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eCompany name\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003e\u003cb\u003eReply S.p.A.\u003c\/b\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eFounded\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003eINFORMATION_NOT_FOUND\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eCountry of origin\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003e🇮🇹 Italy\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eHeadquarters\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003eCorso Francia, 110 – 10143 Turin, Italy\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eUBO\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003eMario Rizzante\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eUBO country\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003e🇮🇹 Italy\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"kv\"\u003e\n\u003cdiv class=\"k\"\u003eDomain registrar country\u003c\/div\u003e\n\u003cdiv class=\"v\"\u003e🇮🇹 Italy\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"display:grid;gap:14px\"\u003e\u003cdiv class=\"company-card\"\u003e\n\u003ch3 style=\"font-size:15px;margin-bottom:10px\"\u003eSocial\u003c\/h3\u003e\n\u003cdiv class=\"social-row\"\u003e\u003ca class=\"social\" href=\"https:\/\/www.linkedin.com\/company\/reply\" target=\"_blank\" rel=\"noopener\" aria-label=\"LinkedIn\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"18\" height=\"18\"\u003e\u003cpath d=\"M16 8a6 6 0 0 1 6 6v7h-4v-7a2 2 0 0 0-4 0v7h-4v-7a6 6 0 0 1 6-6z\"\u003e\u003c\/path\u003e\u003crect x=\"2\" y=\"9\" width=\"4\" height=\"12\"\u003e\u003c\/rect\u003e\u003ccircle cx=\"4\" cy=\"4\" r=\"2\"\u003e\u003c\/circle\u003e\u003c\/svg\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block\" id=\"resources\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eOfficial links\u003c\/span\u003e\u003ch2\u003eResources\u003c\/h2\u003e\n\u003cp class=\"lead\"\u003eAll the official URLs gathered for verification and reference.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"res-grid\"\u003e\n\u003ca class=\"res\" href=\"https:\/\/www.reply.com\/en\/healthcare\/x-rais\" target=\"_blank\" rel=\"noopener\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"10\"\u003e\u003c\/circle\u003e\u003cpath d=\"M12 2a14.5 14.5 0 0 0 0 20 14.5 14.5 0 0 0 0-20\"\u003e\u003c\/path\u003e\u003cpath d=\"M2 12h20\"\u003e\u003c\/path\u003e\u003c\/svg\u003e\u003cdiv class=\"res-text\"\u003e\n\u003cdiv\u003eHomepage\u003c\/div\u003e\n\u003cdiv class=\"url\"\u003ewww.reply.com\/en\/healthcare\/x-rais\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/a\u003e\u003ca class=\"res\" href=\"https:\/\/www.reply.com\/laife-reply\/en\" target=\"_blank\" rel=\"noopener\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"10\"\u003e\u003c\/circle\u003e\u003cline x1=\"12\" y1=\"16\" x2=\"12\" y2=\"12\"\u003e\u003c\/line\u003e\u003cline x1=\"12\" y1=\"8\" x2=\"12.01\" y2=\"8\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003cdiv class=\"res-text\"\u003e\n\u003cdiv\u003eAbout\u003c\/div\u003e\n\u003cdiv class=\"url\"\u003ewww.reply.com\/laife-reply\/en\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/a\u003e\u003ca class=\"res\" href=\"https:\/\/www.reply.com\/en\/contacts\" target=\"_blank\" rel=\"noopener\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003crect x=\"2\" y=\"4\" width=\"20\" height=\"16\" rx=\"2\"\u003e\u003c\/rect\u003e\u003cpath d=\"m22 7-10 5L2 7\"\u003e\u003c\/path\u003e\u003c\/svg\u003e\u003cdiv class=\"res-text\"\u003e\n\u003cdiv\u003eContact\u003c\/div\u003e\n\u003cdiv class=\"url\"\u003ewww.reply.com\/en\/contacts\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/a\u003e\u003ca class=\"res\" href=\"https:\/\/www.reply.com\/en\/privacy-policy\" target=\"_blank\" rel=\"noopener\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cpath d=\"M12 22s8-4 8-10V5l-8-3-8 3v7c0 6 8 10 8 10z\"\u003e\u003c\/path\u003e\u003c\/svg\u003e\u003cdiv class=\"res-text\"\u003e\n\u003cdiv\u003ePrivacy policy\u003c\/div\u003e\n\u003cdiv class=\"url\"\u003ewww.reply.com\/en\/privacy-policy\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/a\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block\" id=\"faq\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eFAQ\u003c\/span\u003e\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq\"\u003e\n\u003cdetails\u003e\u003csummary\u003eWhat does X-RAIS do? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eIt is a medical image analysis AI platform based on neural networks and radiomics. It analyses images acquired by diagnostic equipment, automatically suggests and classifies suspicious areas, and supports the physician at the diagnosis and reporting stages.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eWhich imaging modalities does it cover? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eThe platform is verticalised to different diagnostic methods, including radiography, ultrasound, CT and MRI, and to specific anatomical regions. Three specialisations are described as delivered: mammography, chest radiography and 3D brain MRI for glioma.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eDoes X-RAIS replace the radiologist? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eNo. Reply presents it as a cognitive assistant and states that the system is designed with a human-in-the-loop approach, keeping the radiologist at the centre of the process.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eHow does it integrate with hospital systems? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eThrough DICOM node integration with the RIS and PACS, plus technology modules such as APIs and Web Services; a July 2025 announcement adds APIs compliant with FHIR standards. Identified lesions and reports are returned to the PACS.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eHow much does X-RAIS cost? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eNo price is published. The publisher states only that the platform can be used on a pay-per-use or periodic subscription basis, so any figure has to be obtained through a quotation.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eCan it be installed on our own premises? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eYes, in specific cases: the publisher says the architecture of X-RAIS also allows on-prem installation or use. Otherwise the cognitive and AI services are delivered through cloud architectures.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eIs there a free trial or a demo? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eNo trial and no demonstration are published. The only entry points are the Laife Reply contact form and the Reply contacts page.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eWho publishes X-RAIS? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eIt is developed by Laife Reply, the healthcare unit of the Reply group. The legal identity published on the site is Reply S.p.A., Corso Francia 110, Turin. The site is inconsistent about Laife Reply's status, calling it a business unit of the group on the product page and a company within the group in the July 2025 announcement.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eIs there a documented API? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eAPIs are advertised, as technology modules on the product page and as FHIR-compliant APIs in the July 2025 announcement, but no API documentation page is published.\u003c\/div\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003eWhere is the data hosted? \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"14\" height=\"14\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/svg\u003e\u003c\/summary\u003e\u003cdiv class=\"ans justify\"\u003eThis is not specified. The publisher announces cloud architectures and an on-prem option, without naming a provider, a country or a region.\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003csection class=\"block conclusion\" id=\"conclusion\"\u003e\u003cdiv class=\"head\"\u003e\n\u003cspan class=\"eyebrow\"\u003eConclusion\u003c\/span\u003e\u003ch2\u003eShould you pick X-RAIS?\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rich justify\" style=\"max-width:80ch\"\u003e\n\u003cp\u003eX-RAIS is clinically substantial and commercially opaque, and a buyer should weigh those two things separately. On the clinical side the substance is real: three delivered specialisations across three imaging modalities, named scientific partners in IRCCS IEO, ICS Maugeri, ULLS2 Marca Trevigiana and the University of Pavia, a first-party scientific publication on microcalcification annotation, and a design that keeps the radiologist in the loop rather than automating the decision. The architecture is built for hospitals that already run a PACS and a RIS: a DICOM node, API and Web Services modules, FHIR-compliant APIs, and results pushed back into the PACS where radiologists already work.\u003c\/p\u003e\n\u003cp\u003eOn the commercial side, almost nothing is public. There is no price, no free trial, no demonstration, no API documentation, and no privacy policy or data processing agreement specific to the product. The legal documents on reply.com cover the website and the client contractual relationship, not the handling of clinical images. Nor is there any statement of where data is hosted, any subprocessor list, any certification, or any mention of CE marking or medical device status.\u003c\/p\u003e\n\u003cp\u003eThe realistic buyer is an institution rather than an individual: a radiology department or health authority with the IT capability to integrate a DICOM node and the procurement capability to run a scoped project with Laife Reply. Before signing, three questions deserve to be put in writing: which legal entity actually contracts, since the Privacy Notice (Client) names only \"the Reply Group's Company, holder of the contractual relationship\"; what the regulatory status of the software is for diagnostic support in Europe; and where clinical data is processed and stored. The product page dates from December 2023, so it is also worth asking the publisher which specialisations are current today.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"cta-row\"\u003e\u003ca class=\"btn btn-primary\" href=\"https:\/\/www.reply.com\/en\/healthcare\/x-rais\" target=\"_blank\" rel=\"noopener\"\u003e\u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" width=\"16\" height=\"16\"\u003e\u003cpath d=\"M15 3h6v6\"\u003e\u003c\/path\u003e\u003cpath d=\"M10 14 21 3\"\u003e\u003c\/path\u003e\u003cpath d=\"M18 13v6a2 2 0 0 1-2 2H5a2 2 0 0 1-2-2V8a2 2 0 0 1 2-2h6\"\u003e\u003c\/path\u003e\u003c\/svg\u003e Visit X-RAIS\u003c\/a\u003e\u003c\/div\u003e\u003c\/section\u003e\n\u003c\/div\u003e","brand":"Reply S.p.A.","offers":[{"title":"Default Title","offer_id":58389770207563,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1038\/0905\/7099\/files\/official-reply-x-rais-by-guidaio_babd281e-a00b-4371-bca9-5cb3f696ddad.png?v=1788735009","url":"https:\/\/guidaio.com\/products\/reply-x-rais","provider":"Guidaio","version":"1.0","type":"link"}