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Image Restoration · Image Generators

BoneMRI

BoneMRI is cloud software that reconstructs CT-like 3D bone images from a dedicated MRI scan, covering the cervical, thoracic and lumbar spine and the pelvic region for adults and adolescents, with no ionising radiation at all.

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Overview

What is BoneMRI?

BoneMRI is image processing software published by MRIguidance B.V., a medical technology company based in Utrecht, the Netherlands. It takes a dedicated MRI acquisition and reconstructs a three-dimensional image whose bone contrast resembles that of a CT scan, including quantitative Hounsfield Unit values, without exposing patients or staff to ionising radiation. Because the source is an MRI examination, a single scan yields both bone and soft tissue, and the resulting series are intrinsically registered to one another. The reconstruction relies on deep learning. The model was trained and validated on real patient data collected through clinical studies spanning several hospitals, countries, scanner manufacturers, field strengths and patient populations. Coverage extends to the cervical, thoracic and lumbar spine and to the pelvic region, for adults and for adolescents aged twelve and over. A dedicated adolescent configuration addresses total spine and pelvic imaging where dose reduction matters most, and an optional Synthetic T1w output derives three distinct contrasts from one source acquisition. Operationally, BoneMRI is a cloud service rather than a workstation application. A gateway module, delivered as a Windows installer, sits inside the hospital network, removes protected health information and forwards the study to the vendor's cloud. Reconstruction is triggered automatically once source data reaches the PACS and typically completes in five to fifteen minutes, with results returned to the PACS for viewing in any DICOM-compatible software. The product works with Philips, Siemens and GE scanners at 1.5 T and 3 T, and can also be obtained through the Siemens Healthineers Digital Marketplace. The regulatory position is unusually well documented for a directory entry. BoneMRI is CE certified as a class IIa medical device under the EU Medical Device Regulation and cleared for the United States market via FDA 510(k). The manufacturer holds ISO 13485 for quality management and ISO 27001 for information security. The product carries UDI-DI 08720892675538, the BoneMRI name is a registered trademark in the US, UK and EU, and two United States patents are listed. Instructions for use and DICOM conformance statements are published as PDFs for every release, currently version 1.12. Limits are stated plainly: no acute settings, no tumour work, and reduced reliability near metal implants.

What it does

  • Reconstruct a 3D CT-like bone image from a dedicated MRI acquisition, with no ionising radiation
  • Deliver quantitative Hounsfield Unit contrast and geometrically accurate bone morphology
  • Cover the cervical, thoracic and lumbar spine and the pelvic region in adults and adolescents
  • Produce Synthetic T1w images, giving three distinct contrasts from a single source acquisition
  • Stitch adjacent spinal regions into one continuous total-spine image
  • De-identify studies inside the hospital network before any data reaches the cloud
  • Return finished reconstructions automatically to the hospital PACS, typically in five to fifteen minutes
Audience

When to use BoneMRI / When not to

A quick filter to help you decide if BoneMRI is the right fit.

When to use BoneMRI

  • Radiologists reporting spine and pelvic studies who want bone detail and soft tissue from one examination
  • Orthopaedic and spine surgeons preparing surgical planning or image-guided navigation
  • Paediatric and adolescent care teams treating scoliosis or hip dysplasia, where dose reduction matters most
  • Rheumatologists following spondyloarthritis, erosions or avascular necrosis over repeated examinations
  • Hospital imaging departments looking to remove a preparatory CT from an existing MRI pathway

When not to use BoneMRI

  • Emergency and trauma teams: the vendor excludes use in acute settings because of reconstruction time
  • Oncology teams: the instructions for use explicitly exclude diagnosis and monitoring of primary or metastatic tumours
  • Paediatric care below the age of twelve, which falls outside the stated indication
  • Sites imaging heavily instrumented anatomy, where metal signal voids cannot be reconstructed
  • Individuals or small practices expecting a self-service tool: deployment requires a contract, a gateway install and hospital IT involvement
Get started

How to use BoneMRI

A typical end-to-end flow, from setup to results.

  1. Contact the vendor through the demo request form; there is no online sign-up or self-service trial
  2. Agree commercial terms and sign the Data Processing Agreement the vendor concludes with each customer
  3. Install the gateway module, supplied as a Windows installer, on hospital infrastructure
  4. Open outbound HTTPS access on port 443 to the vendor cloud domain and its subdomains
  5. Secure the gateway host, which may hold protected health information, with disk encryption and strict access control
  6. Configure the MRI protocol and name the DICOM series following the required BoneMRI naming convention
  7. Acquire the dedicated sequence on a supported Philips, Siemens or GE scanner at 1.5 T or 3 T
  8. Let the gateway de-identify the study and forward it automatically once data reaches the PACS
  9. Retrieve the reconstruction from the PACS after roughly five to fifteen minutes
  10. Read bone and soft tissue together, or export to surgical planning and navigation software
Quick read

Pros & Cons

Pros

  • Removes the ionising radiation of a bone CT, which is the clearest benefit for adolescents and repeat imaging
  • One examination returns both bone and soft tissue, with series intrinsically registered together
  • Regulatory status is strong and verifiable: class IIa CE marking under MDR, FDA 510(k), ISO 13485 and ISO 27001
  • Fits an existing radiology workflow through PACS and DICOM, with no dedicated reading station
  • Works across the three main MRI manufacturers at both 1.5 T and 3 T without extra hardware
  • The algorithm is frozen after deployment, so behaviour is reproducible and does not drift silently
  • Instructions for use and DICOM conformance statements are published and versioned back to release 1.1

Cons

  • No price is published anywhere: no pricing page exists and no amount appears on the site
  • No terms and conditions and no legal notice are published, so the contractual relationship is invisible
  • Availability is limited to the EU, UK and US markets, with a Swiss registration; nothing is offered elsewhere
  • Excluded from acute settings and from tumour diagnosis or monitoring by the vendor's own instructions
  • Metal implants create signal voids that cannot be reconstructed into CT-like data
  • Deployment is heavy: a gateway install, firewall changes and coordination with hospital IT
  • The clinical cloud's hosting location is never disclosed, and the ISO certificates are only available on request
Pricing

Pricing & Plans

No pricing is published. The site contains no pricing page and no monetary amount of any kind, and the only commercial call to action is a demo request form. BoneMRI is therefore sold on a quotation basis, and no free plan or free trial is announced or denied. Prospective customers must contact the vendor to obtain terms. In the United States a Medicare billing code (HCPCS G-Code) was obtained in 2025, which governs reimbursement of the examination and should not be read as a licence price.

Prices and plans listed above may evolve. Always check the official pricing page before subscribing.
Trust & Privacy

Data, GDPR & hosting

A consolidated view of how BoneMRI handles your data.

GDPR overview

GDPR compliance is claimed explicitly. The FAQ states the product complies with HIPAA, EU GDPR and the UK Data Protection Act, and every page carries a footer reading CE, FDA, ISO 13485, GDPR and ISO 27001. A Data Protection Officer is appointed and reachable at dpo@mriguidance.com, with a thirty-day response commitment, and the Dutch supervisory authority is named for complaints. Access, rectification, erasure, restriction, objection and portability rights are all listed. As the publisher is established in the Netherlands, no Article 27 representative is required or designated. Two documents coexist and do not agree: a privacy policy dated 3 January 2025 promises processing inside the EEA only, while a template privacy statement dated 17 March 2026 lists a purpose headed selling or sharing data with a third party.

Who owns the data?

No terms and conditions are published, so ownership of the reconstructed images is never stated. What the site does establish is the processing chain: a gateway installed inside the hospital removes protected health information and pseudonymises the study before anything leaves the hospital network, keeping only the indirect identifiers needed for reconstruction. The vendor states that a Data Processing Agreement is signed with every customer, which is where the detailed terms are said to live. For website, newsletter and recruitment data, the privacy policy dated 3 January 2025 names MRIguidance B.V. as responsible under the GDPR and appoints a Data Protection Officer.

Reuse rights

The site publishes no terms and conditions, so there is no public statement on whether a customer may reuse outputs freely. On the vendor's own use of data, two points are explicit. First, the reconstruction service processes studies solely to generate BoneMRI and Synthetic T1w images, which are returned to the hospital PACS. Second, the algorithm is frozen at deployment: it does not change after validation or installation and does not learn from data acquired at a customer site. Historic training used real patient data gathered through clinical studies across several hospitals, countries, scanner vendors and field strengths, which is a distinct matter from any ongoing use of a customer's images.

Data retention & training

Retention summary
Retention is documented for website data only. The privacy policy dated 3 January 2025 states that data is kept no longer than necessary for the purpose it was provided for, after which it is destroyed or de-identified unless the law requires retention. The template privacy statement dated 17 March 2026 says instead, for each of its five stated purposes, that data is retained until the service is terminated. Requests to exercise data subject rights receive a response within thirty days. No retention period is published for patient images processed by the clinical cloud, and the site does not say how long reconstructions or source studies are kept after delivery to the hospital PACS.
Trains on customer data
No
DPA available
Yes
GDPR contact

Hosting summary

Two different scopes must be kept apart. For website, newsletter and recruitment data, the privacy policy dated 3 January 2025 states that everything collected is processed within the European Economic Area only and is not shared outside it without explicit prior consent; a Data Processing Agreement with Google covers analytics, and full IP addresses are blocked. For clinical data, the picture is thinner. Protected health information is removed inside the hospital before anything is sent, and the gateway pseudonymises studies before they leave the hospital network, but the site never names the country, region or provider hosting the clinical cloud that performs the reconstruction. No subprocessor list is published for the product. The European Economic Area commitment found on the site should therefore not be read as a statement about where patient images are stored. The website itself resolves to an address in the Netherlands, which describes the marketing site only.

Hosting regions
EEA
Availability

Where BoneMRI works

Country-level availability.

Available in

AUTBELBGRHRVCYPCZEDNKESTFINFRADEUGRCHUNIRLITALVALTULUXMLTNLDPOLPRTROUSVKSVNESPSWEGBR🇺🇸 United StatesCHE
Watch-outs

Things to keep in mind

Risks and trade-offs to weigh before adopting BoneMRI.

  • Automation bias: reconstructions arrive in the PACS automatically, which can invite reading them as ground truth rather than as a derived, model-generated image
  • A CT-like image is not a CT: the contrast is synthesised from MRI data, and treating the two as interchangeable outside the validated indications is a clinical risk
  • The site's two privacy documents disagree, one promising EEA-only processing and no sharing without consent, the other listing a purpose about selling or sharing data with a third party
  • The hosting location of the clinical cloud is never disclosed, so the jurisdiction that governs patient images cannot be verified from the site
  • Ownership of the reconstructed images is nowhere addressed, because no terms and conditions are published
  • Certifications and accreditations displayed by the hospitals, clinicians and scanner manufacturers referenced on the site belong to those third parties and say nothing about this product
  • Skill erosion: routinely delegating bone assessment to a generated series may reduce familiarity with the underlying MRI signal it is derived from
Setup

Setup & Integrations

Technical difficulty

Moderate to high, and firmly an IT project rather than a sign-up. A gateway module supplied as a Windows installer must be deployed on hospital infrastructure, outbound HTTPS access opened to the vendor cloud, and the gateway host secured with disk encryption and strict access control because it can hold protected health information. MRI protocols and DICOM series naming must follow the vendor's convention, and localising a series name requires a vendor service engineer. Once in place, daily use is effortless: reconstruction is triggered automatically and needs no per-examination action.

Integrations

PACS DICOM Philips Siemens GE Siemens Healthineers teamplay
Company

Behind BoneMRI

Company name
MRIguidance B.V.
Founded
INFORMATION_NOT_FOUND
Country of origin
🇳🇱 Netherlands
Headquarters
Maliesingel 23, 3581 BG Utrecht, The Netherlands
US office
228 E 45th Street, Suite 9E, New York, NY 10017, USA
UBO
INFORMATION_NOT_FOUND
UBO country
INFORMATION_NOT_FOUND
Domain registrar country
🇨🇦 Canada
Support contact

Fundraising

16 October 2018: seed round of EUR 1.5 million led by health-tech investor Health Innovations, through Health Innovations Fund III, together with a strategic informal investor, to fund clinical validation and market roll-out
9 July 2020: bridge round of EUR 750,000 from EIT Health and existing shareholders, after selection from 121 applicants as a best-in-class European healthcare innovation
25 August 2021: USD 1.25 million from United States venture capital firm Mammoth Scientific, through Mammoth Private Capital, to prepare the US market roll-out

Social

Official links

Resources

All the official URLs gathered for verification and reference.

FAQ

Frequently asked questions

What does BoneMRI actually produce?
It reconstructs a three-dimensional image with CT-like bone contrast, including quantitative Hounsfield Unit values, from a dedicated MRI acquisition. Because the source is an MRI scan, bone and soft tissue come from the same examination and no ionising radiation is involved.
Is BoneMRI an approved medical device?
Yes. It is CE certified as a class IIa medical device under the EU Medical Device Regulation and is cleared for the United States market through FDA 510(k). The manufacturer also holds ISO 13485 for quality management and ISO 27001 for information security.
Which anatomies and scanners are supported?
The cervical, thoracic and lumbar spine and the pelvic region are covered. The software works with Philips, Siemens and GE scanners at 1.5 T and 3 T, and requires no additional hardware.
Which patients can be imaged?
Adults and adolescents aged twelve and over who are suspected of conditions involving the bony anatomy. A dedicated adolescent configuration exists for total spine and pelvic imaging, where reducing radiation dose matters most.
How long does a reconstruction take?
The job is triggered automatically as soon as the source data reaches the PACS. Reconstruction times vary with the size of the field of view but are typically between five and fifteen minutes.
How is it integrated into a hospital?
It runs as a cloud service. A gateway module, delivered as a Windows installer, is placed inside the hospital network, removes direct patient identifiers and forwards the study to the cloud. Results return automatically to the PACS. It can alternatively be obtained through the Siemens Healthineers Digital Marketplace.
Are patient images used to train the algorithm?
No. The vendor states that the algorithm is frozen at the time of deployment, does not change after validation or installation, and does not learn from new input data acquired at a customer site. Historic training used patient data collected through clinical studies.
What does it cost?
No price is published. There is no pricing page and no amount appears anywhere on the site; the product is sold by quotation following a demo request. No free plan or free trial is announced.
Where is BoneMRI available?
The FAQ states the EU, UK and US markets. The instructions for use are organised for the EU, UK and Switzerland on one side and the United States on the other, and a Swiss market registration was obtained in 2025.
When should BoneMRI not be used?
It must not be used in acute settings because of the acquisition and reconstruction time required, and it must not be used for diagnosis or monitoring of primary or metastatic tumours. Signal voids near metal implants also cannot be reconstructed into CT-like data.
Conclusion

Should you pick BoneMRI?

BoneMRI is a narrow, serious product with an unusually complete and checkable regulatory file. The promise is easy to state and hard to dismiss: obtain the bone detail of a CT from an MRI examination, and remove the ionising radiation along with the second appointment. For adolescent spine work, repeat follow-up and surgical planning, that is a substantive clinical argument rather than a marketing one, and the class IIa CE marking, the FDA 510(k) clearance, the published instructions for use and the versioned DICOM conformance statements all support it. The reservations are commercial and documentary rather than clinical. No price appears anywhere on the site, no terms and conditions are published, and the ISO certificates are only supplied on request, so a prospective buyer cannot assess the offer without entering a sales conversation. Deployment is not light either: a gateway must be installed inside the hospital, firewall rules opened and DICOM naming conventions respected, which makes hospital IT a necessary participant rather than an afterthought. Availability is also bounded, covering the EU, UK and US markets plus a Swiss registration, and the two privacy documents on the site do not tell the same story about sharing data with third parties. The vendor is refreshingly explicit about what the product must not do. It is excluded from acute settings and from tumour diagnosis and monitoring, it is limited to patients aged twelve and over, and it degrades near metal implants. Stating those limits plainly is a mark of confidence rather than weakness. Read as what it is — a regulated imaging component bought by a department, not a tool an individual signs up for — BoneMRI looks well built and honestly presented, provided the buyer accepts a quotation-based purchase and a genuine integration project.